Cellular energy in neurons
In cultured neurons, red and near-infrared light supported cytochrome c oxidase activity and cellular energy metabolism. This work examines a biological mechanism central to the Neuroenergetics pillar.
THE SCIENCE BEHIND YOUR CAREExplore the research behind the four pillars of Brain Restoration: Neuroenergetics, Brain Oxygenation, Metabolic Healing, and Network Resetting. These selected publications connect the framework in Restoring Brain Health with the science of light, oxygen, nutrition, and rehabilitation.
Pillar 1: Neuroenergetics
Low-level laser therapy and photobiomodulation are studied for their effects on cellular energy and brain function.
Cognition after chronic mild traumatic brain injury
Eleven adults with chronic mild traumatic brain injury received 18 sessions of transcranial red and near-infrared LED treatment. Testing showed improvements in executive function, verbal learning, and memory over the follow-up period.
Pillar 2: Brain Oxygenation
Hyperbaric oxygen research examines the relationship between oxygen availability, brain activity, and functional recovery.
Cognition and quality of life after concussion
In 56 adults with persistent symptoms one to five years after mild traumatic brain injury, 40 hyperbaric oxygen sessions using 100% oxygen at 1.5 ATA were followed by improvements in cognitive function and quality of life. Brain imaging findings corresponded with the cognitive changes.
Neurological function after stroke
Adults six to 36 months after stroke completed 40 hyperbaric oxygen sessions using 100% oxygen at 2 ATA. The researchers reported improvements in neurological function, activities of daily living, and quality of life after treatment, with corresponding changes on brain imaging.
Pillar 3: Metabolic Healing
Research on nutrition and lifestyle connects metabolic health with cognitive performance and the foundations of healthy aging.
The FINGER multidomain lifestyle trial
This two-year trial enrolled 1,260 older adults at increased risk of cognitive decline. A coordinated program of nutrition, exercise, cognitive training, and vascular risk monitoring produced greater improvement in overall cognitive performance than general health advice.
Creatine and cognitive performance
In 45 young vegetarian adults, six weeks of creatine supplementation improved working-memory and reasoning-test performance compared with placebo. The study highlights the connection between brain energy availability and cognitive performance.
Pillar 4: Network Resetting
Neurofeedback and targeted rehabilitation use feedback, movement, and repeated practice to train specific brain and body functions.
Cervical and vestibular rehabilitation after concussion
Among young people with persistent dizziness, neck pain, or headaches after sport-related concussion, adding cervical and vestibular rehabilitation shortened the time to medical clearance. Within eight weeks, 73% of the treatment group and 7% of the control group were cleared to return to sport.
Vestibular rehabilitation for balance and gaze stability
This guideline identifies strong evidence for supervised vestibular rehabilitation in adults with peripheral vestibular hypofunction. It supports targeted exercise to improve symptoms, gaze stability, postural control, and daily function.
Neurofeedback and selected cognitive functions
A double-blind pilot study trained older adults to increase peak alpha frequency using EEG neurofeedback. The reported findings suggested improvements in processing speed and executive function, offering a research example of feedback-based brain training.
Connecting research to your care
Your history, examination, and goals guide the selection of therapies and the measures we use to track your progress. Our team explains the recommended tools and follows changes in symptoms, clinical measures, and everyday function.
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